Known for her work on the hit series "Will & Grace" and the recent Broadway production of Young Frankenstein, Mullally stars as a freewheeling single mom, Rosemary, whose nontraditional parenting style lands her with a son far more responsible than she is. Cheryl Hines ("Curb Your Enthusiasm") co-stars as a recently divorced mother who is raising a pre-teen daughter and a newborn with the help of her "manny" ("SNL" star Horatio Sans), while Jessica St. Clair ("For Your Consideration") portrays the perfect stay-at-home mom with two kids.

Based on the web series of the same title, "In the Motherhood" will take inspiration from real-life stories of motherhood that can be submitted and shared through the show's official website, inthemotherhood.com.

A two-time Emmy Award winner for her portrayal of Karen Walker on NBC's "Will & Grace," Mullally's credits include the Broadway revivals of How to Succeed in Business Without Really Trying and Grease!, as well as the Mel Brooks musical Young Frankenstein. Mullally and her band, Supreme Music Program, have released the albums "Sweetheart," "Big as a Berry" and their latest, "Free Again!"