A Showtime spokesperson told Playbill.com that Patrick Breen, Harvey Fierstein and Barbara Barrie will all be part of the new season.

Breen, who can be seen on Broadway in Next Fall, will guest star in episode four, which airs April 12. Multiple Tony winner Fierstein will guest in the eighth episode, which airs May 10. And, original Company star Barrie will be seen in the seventh episode, which airs May 3.

"Nurse Jackie" airs Monday nights at 10 PM ET on Showtime; check local listings.

Falco stars as the title character Jackie O'Hurley, who is described as "a strong-willed and brilliant — but very flawed — emergency room nurse in a complicated New York City hospital. A lapsed Catholic with an occasional weakness for Vicodin and Adderall to get her through the days, Jackie keeps the hospital balanced with her own kind of justice. Every day is a high wire act of juggling patients, doctors, fellow nurses and her own indiscretions."

The first season saw guest appearances by Blythe Danner, Judith Ivey, Swoosie Kurtz and Elizabeth Marvel, among others. Scott Ellis (Curtains) directed a couple episodes.

Falco has appeared on Broadway in Frankie & Johnnie in the Clair de Lune, 'night, Mother and Side Man.

Falco will return to the New York stage in May opposite Alison Pill will in the Naked Angels production of Chloë Moss' This Wide Night.

For more information, visit sho.com/nursejackie.