Martin and Moore will be joined on the cover by MSNBC anchor Rachel Maddow, Olympic figure skater Johnny Weir and designer and TV host Nate Berkus.
The Out 100 is an annual recognition of entertainers and public figures who have made major strides in the LGBTQ community.
Martin is quoted in the issue as saying, “I am Hispanic, and I am a gay man, and they both struggle. Is it a big responsibility? It can be as big as I want it to be.”
Moore said of her recent movie, "The Kids Are All Right," in which she played one half of a lesbian couple raising a family, “I don’t think a movie like 'The Kids Are All Right' could be made if this wasn’t the way that families are living today all over the United States." The actress also works as an AIDS activist; she said, "I choose a part because I’m interested in the role, the director, the script. I don’t go looking for something that seem political, but by virtue of the roles being intensely personal, it becomes that way.”