The 9 PM show will also feature guests Jessica Vosk, James Carpinello, Zak Resnick, Nikka Lanzarone, Robyn Adele Anderson, Ephraim Sykes and Natalie Tenenbaum.
The Skivvies' Splashdance is presented as part of the duo's monthly residency at 42West.
The Skivvies are known for their acoustic performances of pop songs, wearing nothing but their underwear. Lauren Molina, Nick Cearley and their guests play instruments ranging from the cello, ukulele, guitar and glockenspiel to the melodica.
General admission tickets begin at $20, with reserved seating available for $35 and VIP at $85. A full bar and a la carte menu will be available at the show. For tickets, visit 42WestNY.com. 42West is located at 514 West 42nd Street, between 10th and 11th Avenues.