The upcoming Talk Radio and recent Glengarry Glen Ross star will first appear in the series an episode titled "Sweet Jane."

Playing the recurring role of Michael Keppler, Schreiber's character is described as "a seasoned CSI who has established a strong reputation in various police departments across the country before joining the veteran team at the Las Vegas Crime Lab."

"Catherine and the rest of the CSI team find it challenging to get a good read on their new member as he joins them in tracking a recently active serial killer who has been killing since the 1970s," reads a CBS episode description. Fellow stage vets Ned Beatty (Cat on a Hot Tin Roof) and Chris Bauer (A Streetcar Named Desire, Defiance) will guest star.

Schreiber previously stated, "After meeting the people who run 'CSI,' it immediately becomes apparent why it has consistently been one of the top shows on television. I am a fan, how could I say no?"

The actor will still star in the upcoming Broadway staging of Eric Bogosian's Talk Radio, which begins previews Feb. 9. Schreiber earned his Tony Award for his turn in Glengarry Glen Ross. His previous work on television has included the HBO film "Lackawanna Blues" as well as the made-for-television movies "RKO 281" and "Spinning Boris." Schreiber followed his 2003 turn in Henry V for The Public Theater's "Shakespeare in the Park" series with this past summer's staging of Macbeth. Other credits include Harold Pinter's Betrayal, Neil LaBute's The Mercy Seat and Othello. In film, he has been seen in the "Scream" trilogy, "Kate and Leopold," "Ransom" and "The Manchurian Candidate" and made his directorial debut last year with "Everything Is Illuminated" — which he also adapted.

"CSI: Crime Scene Investigation" — which airs Thursdays at 9 PM (ET) — follows a team of Las Vegas-based forensic investigators who solve crimes by examining the evidence. The cast features William Petersen, Marg Helgenberger, Gary Dourdan, George Eads, Paul Guilfoyle, Jorja Fox, Eric Szmanda and Robert David Hall. Schreiber's appearance coincides with a two-episode leave for Petersen. Following its 2000 debut, CBS has already created two spin-offs "CSI: Miami" and "CSI: NY."

For more information, visit CBS' website at cbs.com/csi.