The Off-Broadway play, which will run through Sept. 16, will feature Jenny Bacon (In the Wake), Gary Cole ("Office Space," "The West Wing"), Betty Gilpin (We Live Here), Julianne Nicholson ("Boardwalk Empire," This) and Lois Smith (The Illusion, The Trip to Bountiful, Broadway's Buried Child). Opening night is set for Aug. 27.

Tickets for the initial run of the production are $25 as part of the Signature Ticket Initiative: A Generation of Access, a program that guarantees affordable and accessible tickets to every Signature production for the next 20 years.

In the play, according to Signature, "Sally [played by Nicholson] lives with her mysterious family in a cavernous home overlooking Los Angeles. When a visitor arrives, Sally's dark secrets — and the secrets of those around her — threaten to come into the light."

Pulitzer Prize winner Shepard (A Lie of the Mind, Curse of the Starving Class, True West, Buried Child) was Signature's 1996-97 Playwright-in-Residence.

The production team includes Eugene Lee (scenic designer), Kaye Voyce (costume designer), Tyler Micoleau (lighting designer) and Eric Shimelonis (sound designer). Donald Fried is production stage manager. The Pershing Square Signature Center is located at 480 W. 42nd Street between 9th and 10th Avenues. To purchase tickets, call the Signature Theatre Box Office at (212) 244-7529 or visit SignatureTheatre.org.

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Subscriptions are currently on sale for the 2012-13 season, which will also include plays by David Henry Hwang, Bill Irwin and David Shiner, Regina Taylor, August Wilson and Lanford Wilson.