Metcalf's character, Janie, will work at her family's brewery in the program, which was created by "Will and Grace"'s David Kohan and Max Mutchnik. Janie, who is in her forties, is described as "Ted's attractive and high strung wife, mother to Clay, Kyle, Lizzy and Michael. [S]he's newly sober, and being newly sober at a brewery with a family of brewery workers is not a happy or easy thing. She's also trying to stop swearing, and it's a toss up which vice is more difficult to shed. Though dealing with her own issues, she is still a source of strength to her husband and family."

An air date for "Strange Brew" has yet to be announced.

Metcalf is currently appearing Off-Broadway in Sam Shepard's A Lie of the Mind. An original ensemble member of the Steppenwolf Theatre in Chicago, her New York stage credits include Brighton Beach Memoirs; November, for which she was Tony-nominated; and Balm in Gilead. She received three Emmy Awards for her work on ABC-TV's "Roseanne."