Rose, helmed by Nora artistic director Caroline Reddick Lawson, will play Nov. 21-Dec. 13, with an official opening night scheduled for Nov. 29.

Chalfant, who received a Tony nomination for her performance in Angels in America, will take on the famous matriarch of the Kennedy political clan in the monologue. She outlived her sons President John F. Kennedy and Sen. Robert F. Kennedy, both of whom were assassinated. Set in 1969 at the Kennedy’s Hyannis Port compound, the show sees Rose struggling with all the tragedies the the family has overcome in the light of a third son, Teddy Kennedy's, car accident at Chappaquiddick. She tries to find a new understanding of the choices she made as well as those made by her husband and children.

Leamer's play is inspired by real-life audio recordings Rose Kennedy made for her ghostwritten autobiography. Much of the show is also informed by Leamer's own books about the famous family, including "The Kennedy Women" and "The Kennedy Men: 1901-1963."

Watch a trailer for the play below:

Nora's Playhouse is a theatre company dedicated to producing women's stories and nurturing the career of female artists. "Our women-centered mission results from a recognition that women are still woefully under-represented as directors, playwrights, artistic directors and managers for professional theatre, as well as the primary subject matter for scripts," states the company on its website.

The Clurman Theatre, Theatre Row is located at 410 West 42nd St. Click here to purchase tickets.