Toronto's Tarragon Theatre and Jack in the Black Theatre co-present the world premiere of The Domino Heart, about three unconnected people who seek substance in their lives and find themselves connected by a heart transplant.

Tarragon, the theatre known for Toronto premieres of recent plays as well as new Canadian works, gives the drama by Matthew Edison a home at its Extra Space beginning March 20, followed by a March 25 opening.

This is actor Edison's first work as a playwright. The script was developed by Jack in the Black and its artistic director, Michael Kessler, who helms the staging.

"The transplanted organ is the fulcrum for three otherwise unconnected characters who are searching for substance in their lives," according to production notes. "Cara has recently lost her husband, Peter, in a car accident. Was she a link in the chain of events that led to the accident? Mortimer, an Anglican minister sleepless in his hospital room, faces a critical moment in his past that forever changed his sense of humanity. Leo, in his office on the 62nd floor, is grappling with the ruthlessness of the world he embodies."

The cast includes Raoul Bhaneja, Rosemary Dunsmore and David Fox.