Alexandra Burke stars in the musical based on the Whitney Houston film.
The unnamed woman audience member was asked to leave by Royal Concert Hall staff after cursing and becoming "aggressive to people who told her to shut up." The disturbance lasted a reported 20 minutes before staff stepped in.
Fellow audience member Sacha Gainard told the BBC that the atmosphere "felt more like a football [soccer] match" than a trip to the theatre.
Directed by Thea Sharrock, the tour launched in September 2014 in Southampton.
For full tour dates and to book tickets, visit www.thebodyguardmusical.com.