Joining the previously announced Emmy winner Marlo Thomas, Greg Mullavey and Kate Wetherhead will be George Merrick.
David Saint, artistic director of the George Street Playhouse, where Clever Little Lies made its world premiere in December 2013, will again direct.
"A mother always knows when something is wrong," according to press notes. "When Alice (Marlo Thomas) notices her beloved husband Bill (Greg Mullavey) has returned home on edge after a tennis match with their son, she grows suspicious and springs into action. Determined to piece together the puzzle, she invites her son, Bill, Jr. (George Merrick) and daughter-in-law, Jane (Kate Wetherhead), over for drinks and dessert. Sidesplitting chaos ensues as Alice digs for the truth, resulting in even more honesty than anyone expected."
The creative team will include Yoshi Tanokura (scenic design), Esther Arroyo (costume design), Christopher J. Bailey (lighting design), Scott Killian (sound design and composition) and McCorkle Casting (casting).
Producers are Joan Raffe, Jhett Tolentino and Douglas Denoff.
Tickets can be purchased by visiting Telecharge.com. To order by phone, and for groups of 10 or more, call (212) 239-6200. Tickets will be available at the Westside Theatre Box Office (407 West 43rd Street) starting Sept. 8. For more information visit www.CleverLittleLies.com.