Directed by Nicholas Martin, the production will continue through Oct. 14.

The cast features three-time Oscar nominee Sigourney Weaver, four-time Emmy Award winner David Hyde Pierce, Obie Award winner Kristine Nielsen, Genevieve Angelson, Shalita Grant and Billy Magnussen.

"It’s a lovely day at Vanya (David Hyde Pierce) and his stepsister Sonia's (Kristine Nielsen) farmhouse in Bucks County, PA," according to press notes. "But instead of spending the morning strolling through their cherry orchard, these wacky siblings have their hands full with a prophetic cleaning woman, a neighborhood costume party, and a surprise visit from their movie-star sister Masha (Sigourney Weaver) and her studly new boy-toy, Spike (Billy Magnussen)."

The creative team also includes set designer David Korins, costume designer Emily Rebholz, lighting designer Justin Townsend, composer of original music and sound designer Mark Bennett, casting director Daniel Swee and production stage manager Cheryl Mintz.

A McCarter Theatre commission, Vanya and Sonia... is produced in association with Lincoln Center Theater, where it will play following its Princeton run. Read Playbill.com's recent interview with Durang. The LCT production will begin previews Oct. 25 prior to an official opening Nov. 12 at the Mitzi E. Newhouse Theater (150 West 65th Street).

Christopher Durang’s plays include A History of the American Film (Tony nomination), Sister Mary Explains It All For You (Obie Award), Beyond Therapy, Baby With The Bathwater, The Marriage of Bette and Boo (Obie Award and Guild Hull Warriner Award), Sex and Longing, Laughing Wild, Betty’s Summer Vacation (Obie Award), Miss Witherspoon (produced by McCarter Theatre Center, 2005 Pulitzer Prize finalist) and, most recently, Why Torture Is Wrong, and the People Who Love Them.

For tickets call (609) 258-2787, go to mccarter.org or visit the McCarter Theatre Center Ticket Office at 91 University Place in Princeton.