Burstyn will also star in the piece, which is inspired by events in the life of Thruline Entertainment manager-producer Danny Sherman. "Bathing Flo" is written by actress-writer Lauren Lake, Danny Brocklehurst and Sherman. Erica Steinberg, Lake and Sherman (under Thruline's production banner Tagline Pictures) produce.

The story centers on a man in need of a place to live. When he is offered the chance to housesit in exchange for free rent, he discovers that the house is occupied by the man's elderly mother Flo, who is part of the deal.

Burstyn, an Academy Award winner for "Alice Doesn't Live Here Anymore" and an Emmy winner for "Political Animals," received the Tony for her performance in Same Time, Next Year. She has also been seen on Broadway in Oldest Living Confederate Widow Tells All, Sacrilege, Shimada, Shirley Valentine, 84 Charing Cross Road and Fair Game.