LuPone will co-host the hour-long show, which airs 3 PM-4 PM ET, with regular hosts Jane Hanson, Sara Gore and Jacque Reid; Patinkin will also appear as a guest to talk about An Evening and his hit TV series, “Homeland.”

The 63-performance engagement of An Evening will continue through Jan. 13, 2012.

An Evening With Patti LuPone and Mandy Patinkin, according to press notes, "reunites these Tony Award-winning virtuosos (and lifelong friends) for the first time since Evita. Much more than a concert, this is a unique musical love story told entirely through a masterful selection of the greatest songs ever written for the stage. Funny, passionate, intimate and utterly unforgettable, this is An Evening no fan of musical theatre — or of these two acclaimed performers — can afford to miss."

The orchestra features musical director Paul Ford on piano and John Beal on bass. The production also includes designs by David Korins, lighting design by Eric Cornwell, sound design by Daniel J. Gerhard and costume design by Jon Can Coskunses. Staci Levine, The Dodgers, Jon B. Platt and Jessica R. Jenen produce.

Audiences can expect to hear such tunes as "Another Hundred People," "When," "A Cockeyed Optimist," "Twin Soliloquies," "Some Enchanted Evening," "Getting Married Today," "Loving You," "I'm Old-Fashioned," "I Have the Room Above Her," "Baby It's Cold Outside," " Everybody Says Don't," "A Quiet Thing," "It Takes Two," "I Won't Dance," "I Want a Man," "April in Fairbanks," "Old Folks," "Everything's Coming Up Roses," "Buddy's Blues," "The Hills of Tomorrow," "Merrily We Roll Along," "Old Friends," "Like It Was," "Oh What a Circus," "Don't Cry for Me Argentina," "Somewhere That's Green," "In Buddy's Eyes," "You're a Queer One, Julie Jordan," "If I Loved You," "What's the Use of Wond'rin'" and "You'll Never Walk Alone."