Wallace's best-known opera is Harvey Milk, which told the story of the murder of the openly gay San Francisco city supervisor. It premiered in 1995 at Houston Grand Opera and was also seen at San Francisco Opera.
The Bonesetter's Daughter is set in China before the communist revolution, as recalled by an elderly Chinese mother in modern-day San Francisco. The libretto will be written by the author; Chen Shi-Zheng will direct. The opera will also be premiered in China in 2008.