Jenny Sullivan directs the classic about love, longing and missed opportunities that runs through April 17.
Susan Albert Loewenberg produces the engagement, which will be recorded and broadcast on LATW's nationally syndicated radio theatre series, "The Play's the Thing."
In addititon to Thompson ("For Colored Girls") as Irina, Westfeldt (Wonderful Town) as Masha, Zimmerman ("Big Love") as Olga and Hamm ("Mad Men") as Vershinin, the cast features Rebecca Mozo ("Cold Case") as Natasha, Josh Cooke ("I Love You, Man") as Kulygin/Fedotik, Dan Donohue (The Lion King) as Tuzenbach, Pamela Dunlap ("Mad Men") as Anfisa, Marc Halsey ("Brothers and Sisters") as Solyony/Rode, Robert Pine ("Bold and the Beautiful") as Chebutykin/Ferapont and Reid Scott ("The Big C") as Andrei.
For tickets to any of "The Play's the Thing" productions at the Skirball Cultural Center, 2701 N. Sepulveda Boulevard, call the L.A. Theatre Works box office at (310) 827-0889.
For more information visit latw.org.