Variety reports that the Shakespearean work will begin performances at the Donmar Nov. 29 with an official opening Dec. 4. The limited engagement will play through Feb. 23, 2008.

Grandage will direct a cast that boasts Chiwetel Ejiofor in the title role with Ewan McGregor as Iago and Kelly Reilly as Desdemona. All three actors have previously worked with Grandage: Ejiofor in The Vortex in 2002, Reilly in After Miss Julie in 2003, and McGregor in the recent revival of Guys and Dolls.

About the upcoming production, the award-winning director told Daily Variety, "As one of Shakespeare's most intimate plays with one of the smallest casts, it's perfect for the Donmar. The strength of this cast will allow us to explore the internal, as well as the external, life of the play."

The creative team will include Christopher Oram (design), Paule Constable (lighting design) and Adam Cork (composer, sound design).

Grandage also told the industry paper that his 2005 production of Friedrich Schiller's Mary Stuart may be Broadway bound. "Subject to the availability of director Phyllida Lloyd and actresses Janet McTeer and Harriet Walter, we are committed to making this our next Broadway presentation," Grandage said.