The Broadway favorite also missed the April 24 evening performance of the Broadway revival.
Mamie Parris stepped into Chenoweth's role.
In Twentieth Century, Chenoweth, a Tony Award winner for You're a Good Man, Charlie Brown and a Tony nominee for Wicked, plays Lily Garland opposite film, television and Broadway star Peter Gallagher ("The O.C," "American Beauty," Guys and Dolls, The Country Girl) as Oscar Jaffe.
See All the Glamour, All the Drama in These First Pics of Kristin Chenoweth in On the Twentieth Century!
The cast also features Tony nominee Andy Karl (Rocky) as Bruce Granit, Mark Linn‐Baker (You Can't Take It With You) as Oliver Webb, Michael McGrath (Nice Work If You Can Get It) as Owen O'Malley and Tony winner Mary Louise Wilson (Grey Gardens) as Letitia Primrose with Phillip Attmore (After Midnight), Justin Bowen (Chaplin), Preston Truman Boyd (Bullets Over Broadway), Paula Leggett Chase (Bye Bye Birdie), Ben Crawford (Big Fish), Rick Faugno (Show Boat with the New York Philharmonic), Jenifer Foote (The Mystery of Edwin Drood), Bahiyah Hibah (Chicago), Drew King (Broadway debut, On Your Toes at Encores!), Analisa Leaming (Broadway debut, Pipe Dream), Kevin Ligon (Bullets Over Broadway), Erica Mansfield (Pippin), James Moye (Bullets Over Broadway), Linda Mugleston (Cinderella), Mamie Parris (Wicked), Andy Taylor (Once), Jim Walton (The Mystery of Edwin Drood) and Richard Riaz Yoder (White Christmas).
Roundabout associate artistic director Scott Ellis (a six-time Tony Award nominee for She Loves Me, Steel Pier, 1776, Twelve Angry Men, Curtains, The Mystery of Edwin Drood) directs On the Twentieth Century with choreography by Warren Carlyle, a Tony Award winner for After Midnight.
The musical premiered on Broadway in 1978 under the direction of Harold Prince and won Tony Awards for Best Original Score and Best Book of a Musical.
The American Airlines Theatre on Broadway is located at 227 West 42nd Street. For tickets, call (212) 719-1300 or visit RoundaboutTheatre.org.