Presenters for the evening will include Wayne Brady ("Let's Make a Deal"), Jeff Foxworthy ("Are You Smarter Than a 5th Grader?"), Vanessa Marcil ("General Hospital," "Las Vegas"), Alex Trebek ("Jeopardy"), Rachael Ray ("The Rachael Ray Show"), Zack Conroy ("The Bold and the Beautiful"), Jonathan Jackson ("General Hospital"), Dr. Travis Stork, Dr. Drew Ordon, Dr. Jim Sears and Dr. Lisa Masterson, Rebecca Budig ("All My Children"), Sharon Case ("The Young and the Restless"), Michael Easton ("One Life to Live"), Jon Hensley ("As The World Turns"), Kelley Menighan Hensley ("As The World Turns"), Susan Lucci ("All My Children"), Cameron Mathison ("All My Children"), Kimberly Matula ("The Bold and the Beautiful"), Laura McKenzie ("Laura McKenzie's Traveler"), Kelly Monaco ("General Hospital"), Joshua Morrow ("The Young and the Restless"), Ronn Moss ("The Bold and the Beautiful"), Peter Reckell ("Days of our Lives"), Trevor St. John ("One Life to Live"), Louise Sorel ("Days of our Lives"), Montel Williams ("The Montel Williams Show") and the Las Vegas acts Blue Man Group, Cirque du Soleil and the showgirls of Jubilee.
The evening will also feature a performance from the Las Vegas company of The Lion King. Ryan Seacrest will also be on hand to introduce the "American Bandstand" and Dick Clark tribute, with Donny Osmond, Chubby Checker, Tony Orlando and The Jersey Boys scheduled to perform.
Associated Television International (ATI) will produce the show with ATI president and Emmy award-winning producer David McKenzie serving as executive producer. The Daytime Emmy Awards recognize outstanding achievement in all fields of daytime television production.