He will be replaced by the rising young pianist Yundi Li, making his Carnegie Hall recital debut.
According to Perahia's management, the flare-up of an earlier finger injury prompted the cancellation. A statement said, "While he has recovered substantially, doctors advised that it was premature to undertake a ten-city national tour."
Li's program will include Mozart's Sonata No. 10 in C major, Schumann's Carnaval, and Liszt's Sonata in B Minor.
Born in 1982 in China, Li won first prize at the 2000 International Chopin Competition aged 18. In 2001 he signed an exclusive recording contract with Deutsche Grammophon; his first recording for the label was an all-Chopin program.
Tickets for the Murray Perahia recital will be honored at the Yundi Li concert.