Rubin-Vega will be joined by Maria Cellario (The Royal Family) and Flor de Liz Perez (The House that will not Stand) for the June 3-22 engagement.
Current cast members Kate del Castillo, Angélica María and Angélica Vale continue through June 1.
Los Monólogos de la Vagina began Off-Broadway performances May 6 at The Westside Theatre, the production's original Off-Broadway home. The production officially opens May 18.
Morris Gilbert and Federico González Compeán, who are the producers of the long-running Mexico City production of Los Monólogos de la Vagina, present the New York return that is directed by Jaime Matarredona.
Akin to the previous Off-Broadway model, Los Monólogos de la Vagina features a cast of rotating actresses. Colón is the artistic director of the Puerto Rican Traveling Theatre; del Castillo has appeared in "Under the Same Moon" and "The Book of Life"; Angélica María is a Grammy Award-winning musician and actress; and Vale is known for her television hit "La fea mas bella," the Mexican version of "Ugly Betty." The New York production is modeled after the Mexico City production. Portions of tickets sold benefit Ensler's global activism campaign V-Day, which seeks to end violence against women.
The original Obie Award-winning production of The Vagina Monologues played 1,381 performances at The Westside Theatre from 1999 to 2003. It has played in over 140 countries and in over 48 languages. A television version featuring Ensler was produced for HBO in 2002.
Ensler's plays include Necessary Targets, The Treatment, The Good Body and Emotional Creature. Her new play O.P.C. will premiere at the American Repertory Theater in November. She is the recipient of the 2011 Isabelle Stevenson Award.