McDermott will be part of a cast that also includes David Ayers, Pamela Bob, Ashlee Dupré, Stephen Hanna, Natalie Joy Johnson, Howard Kaye, Topher Nuccio, Ronica V. Reddick, Kimberly Stern and Doug Trapp.

Sean McDermott starred on Broadway in Miss Saigon (Chris), Grease (Danny Zuko), Starlight Express (Rusty) and Falsettos (Whizzer). He was one of four Broadway singers handpicked by Barbra Streisand to sing alongside her on her 2007 European tour. McDermott has traveled the world performing with some of the most celebrated symphony orchestras and has shared the stage with Bernadette Peters, Mandy Patinkin, Elaine Stritch, Johnny Mathis and Robert Goulet. His TV credits include “Desperate Housewives,” “Charmed,” “Medium” and “Freddie.”

Silence! features a book by Hunter Bell, music and lyrics by Jon and Al Kaplan and direction and choreography by Christopher Gattelli.

"In the Academy Award-winning film 'The Silence of the Lambs,'" press notes state, "rookie FBI agent Clarice Starling matches wits with the brilliant but insane cannibal, Dr. Hannibal Lecter, to catch the serial killer known only as Buffalo Bill. Clarice faces her own demons while racing the clock to unlock Lecter's clues before another innocent girl is killed and skinned by Buffalo Bill. The laugh-out-loud wicked satire, Silence! The Musical, features a singing chorus of floppy eared lambs narrating the action as Buffalo Bill gleefully dances a hoedown while kidnapping hapless Catherine Martin. Even Dr. Lecter, scary as ever, sings about the life he'd like to lead someday outside the prison walls."

Music supervisor is Mark Hartman, with orchestrations by Brian J. Nash. Silence! is produced Off-Broadway by Theater Mogul.

Elektra Theatre is located at 673 Eighth Avenue at 42nd Street. Tickets are  available by calling (212) 352-3101 or through SilenceTheMusical.com.