Lombardi playwright Eric Simonson directs the production that will run through March 20 at the Skirball Cultural Center.
Keach, who recently starred in Jon Robin Baitz's latest play, Other Desert Cities, at Lincoln Center Theater, is joined by Jane Kaczmarek ("Malcolm in the Middle") as Linda, Steven Culp ("Desperate Housewives") as Biff and John Sloan (King Lear) as Happy.
The cast also features Maureen Flannigan, Jason Henning, Sam McMurray, Kathryn Meisle, Tim Monsion, Kate Steele and Kenneth Williams.
Simonson, a Steppenwolf Theatre Company member, is currently represented on Broadway with the football-centered play Lombardi. It was announced Feb. 17 that Magic/Bird, his account of the relationship between basketball players Larry Bird and Magic Johnson, will arrive on Broadway in 2012.
All productions are recorded and broadcast on LATW's nationally syndicated radio theatre series, "The Play's the Thing."
For tickets to any of "The Play's the Thing" productions at the Skirball Cultural Center, 2701 N. Sepulveda Boulevard, call the L.A. Theatre Works box office at (310) 827-0889.
For more information visit latw.org.