The daily, one-hour show — which tapes in Los Angeles, CA — plays in the New York area on WNBC at 3 PM. Check your local listings. Will Ferrell ("The Producers"), Jenny McCarthy and a 10-year-old Black Belt are the guests scheduled for her television premiere. Eva Mendes, Lisa Kudrow, Carol Burnett (Putting It Together, Once Upon a Mattress), Rainn Wilson (London Assurance) and Felicity Huffman (Speed-the-Plow) are also slated for the first week. Lineups are viewable on www.meganshow.tv

On the first "Megan Mullally Show," the actress opens her show with a musical number set to the tune of Hair's "Aquarius" and title track. The show is expected to feature "a mix of celebrities, real people, music and comedy," according to an NBC release.

Best known for her role as Karen on the NBC series "Will & Grace," Mullally is remembered by theatregoers as Rosemary Pilkington in the 1995 revival of How To Succeed in Business Without Really Trying opposite Matthew Broderick. Her other stage creds include Marty in the 1994 revival of Grease. She has also performed her one woman musical, Sweetheart and numerous concert gigs at Lincoln Center, Kennedy Center, Chicago’s Goodman Theater and elsewhere.

The actress has previously hosted "Saturday Night Live" and subbed for David Letterman on CBS' "The Late Show."

Corin Nelson, Emmy Award-winning veteran daytime producer and former showrunner on "The Rosie O'Donnell Show," serves as Executive Producer. Mullally's band leader will be Brett Simmons. Ken Fuchs serves as director.

For more information and to preview promotional videos, visit www.meganshow.tv or your local NBC affiliate.