Cast members from the George C. Wolfe-directed production will perform the number "I Can Cook, Too" on the daytime talk show.
On the Town is currently in previews at Broadway's Gershwin Theatre.
O'Donnell, famous for inviting theatre talents onto her show, started up her new season Aug. 31, 1998. O'Donnell's show airs in New York on channel 7 at 10 AM. Check local listing for times and stations.