Wetzel assumes the role from original cast member Eddie Korbich, who departs to begin rehearsals to play Scuttle in the new stage production of Disney's The Little Mermaid.
Broadway veteran Wetzel has appeared in The Producers, Thou Shalt Not, Annie Get Your Gun and Ain't Broadway Grand as well as Stephen Sondheim's Opening Doors at Carnegie Hall.
In the show within a show, Wetzel will play a tap-happy best man in a 1920s wedding. His signature number is "Cold Feets."
The Drowsy Chaperone is directed and choreographed by Tony Award nominee Casey Nicholaw (Spamalot), with music and lyrics by Tony Award winners Lisa Lambert and Greg Morrison and a book by Tony Award winners Bob Martin and Don McKellar.
"To chase his blues away, a modern day musical theatre addict known simply as Man in Chair drops the needle on his favorite cast album – the 1928 musical comedy The Drowsy Chaperone," according to the producers. "From the crackle of his hi-fi, the uproariously funny musical magically bursts to life on stage. We are instantly immersed in the hilarious tale of a glamorous bride and her uproarious wedding day, complete with thrills and surprises that take both the cast (literally) and the audience (metaphorically) soaring into the heavens. Man in Chair's infectious love of The Drowsy Chaperone speaks to anyone who has ever been transported by the theatre."
The Drowsy Chaperone plays Tuesday-Saturday at 8 PM with matinees on Wednesday and Saturday at 2 PM and Sundays at 3 PM.