In the Pulitzer Prize-honored, Tony Award-winning tale, the good sister is caught between a tough nun and a charming priest. As previously reported, Meryl Streep will play Sister Aloysius and Philip Seymour Hoffman Father Flynn. The latter is accused of sexually abusing a student in a Bronx Catholic School in 1964.

Shanley will adapt and direct his play for Miramax Films and producer Scott Rudin.

Adams received a 2006 Best Supporting Actress Academy Award nomination for her role in "Junebug."

Manhattan Theatre Club first produced Doubt Off-Broadway in 2004, and it jumped to a Broadway run, a 2005 Tony win and a national tour. The four-actor, 90-minute drama is expected to be a major title in regional theatres in the coming season.

The original cast of the play boasted Cherry Jones as Sister Aloysius, Heather Goldenhersh as Sister James, Brian F. O'Byrne as Father Flynn and Adriane Lenox as Mrs. Muller, the boy's mother. All four were Tony-nominated, and Jones and Lenox won the prize. The play ran 525 performances on Broadway and closed in July 2006. Doug Hughes directed.

Variety previously reported that the film cast will be expanded to include others in the Bronx school community, including the young black student who is the center of the play's controversial accusations. Casting for the role of Mrs. Muller has not been announced.

Location shooting in New York City is expected to start in late 2007.