Chase will play the role of Flood in the program, which airs at 10 PM ET.
The series cast features Tom Selleck, Bridget Moynahan, Donnie Wahlberg, Will Estes, Len Cariou and Jennifer Esposito.
"When a bank robbery goes awry and turns into a hostage situation, Frank (Tom Selleck) realizes that the perp is a former cop and old friend who has resorted to crime because of his daughter's desperate illness," according to press notes for the episode.
Chase's recent television appearances include "Pan Am," "White Collar," "Rescue Me" and "Royal Pains."
For more information visit http://www.cbs.com/shows/blue_bloods.