Opened on January 11, 1927, the theatre was one of six legitimate theatres built by the Chanin Brothers in the 1920s.
Over the years it bore the names John Golden Theatre and Royale Theatre (twice) but was rechristened after the longtime president of the Schubert Organization in 2005.
Design by Herbert J. Krapp, the theatre was done in modern Spanish style and had two murals, collectively titled Lovers of Spain, by Willy Pogany.
In 1937, after the departure of producer John Golden, who later leased the Masque Theatre next door and rechristened it the John Golden Theatre, the Bernard B. Jacobs theatre ceased functioning as a legitimate playhouse and became the CBS Radio Theatre.
In October 1940, the theatre was taken over by the Magoro Operating Corporation, who restored it back to a playhouse.
Throughout it's history, the Bernard B. Jacobs theatre has been the home of iconic performers including Mae West, Julie Andrews, Bernadette Peters, and more.