Ashford is joined by songwriter and music director Will Van Dyke and The Whiskey 5 band for the performances.
In addition to the March 21 launch at the Broadway Playhouse in Chicago, Ashford will also play The Denver Center for the Arts in Denver, April 11-12; The Venetian Room at the Fairmont Hotel in San Francisco April 19; and The Smith Center for the Performing Arts in Las Vegas, June 27-28.
Here's how it's billed: "Lost in the Stars celebrates the classic cabaret with an eclectic mix of music from the disco days of Donna Summer, to Judy at Carnegie Hall, to a sing-a-long of Alanis Morrisette, as well as the haunting melodies of Stephen Sondheim and Kurt Weill. They are all woven together through fabulous, funny and most of all heartfelt storytelling. After this glossy and glittery evening with a special appearance by the Sun and the Moon, you will be sure to get 'Lost in the Stars.'"
Ashford, whose credits also include Wicked, Legally Blonde and the Off-Broadway revival of Rent, earned a Tony Award nomination for her work in Kinky Boots. She can also be seen on Showtime's "Masters of Sex."