It will be directed by David Mercatali, associate director at the theatre, who also staged Ridley's Tender Napalm there in 2011.
Feathers in the Snow is described in press materials as an "epic story of magic and migration. Covering over five hundred years - and with a huge cast - it explores how stories give meaning to random events and our constant need to find somewhere we call 'home'."
The theatre will be temporarily relocating to new premises while development work is carried out to London Bridge station that runs overhead. More details on the new venue are to be announced in October.
Casting and further creative details are to be announced.
To book tickets, contact the box office on 020 7407 0234, or visit www.southwarkplayhouse.co.uk.